Upon registration, isocycloseram will provide insect management in cotton, vegetables, tree fruit and more.

GREENSBORO, N.C., USA, April 16, 2025 ― Syngenta announced the names of three foliar-applied insecticide brands for its in-season insect management portfolio in the U.S. today. Upon approval by the Environmental Protection Agency, these foliar insecticide products are anticipated to manage insect pests in cotton, vegetables, tree fruit crops and more.
“We’re committed to creating solutions that meet the evolving needs of growers,” said Syngenta Technical Product Lead Elijah Meck, Ph.D. “With pests becoming more difficult to control, this active ingredient will provide growers with a new option.”
Isocycloseram, which has been approved for use in other countries, will act by contact and ingestion, providing rapid feeding cessation. Leveraging this novel active ingredient in IRAC Group 30, will also provide growers with a new resistance management option.

Watch this video to learn how the novel mode of action works through contact and ingestion when foliar-applied to deliver management of insects at all growth stages.
Upon EPA registration, foliar-applied products using PLINAZOLIN® technology will be sold under the following brand names:
- Incipio™: a foliar-applied insecticide intended for use in brassica, cucurbit, leafy and fruiting vegetable crops that will provide control of a broad spectrum of pests.
- Vegetables ― Diamondback moth, melonworm, pepper weevil, pickleworm, thrips, other lepidopterous pests
- Vertento®: a foliar-applied insecticide intended for use in cotton, peanuts and onions that will deliver control of various insect pests including plant bugs, thrips and mites.
- Cotton ― Plant bugs, stink bugs, thrips
- Onions ― Thrips
- Peanuts ― Mites, thrips
- Zivalgo™: a foliar-applied insecticide intended for use in pome and stone fruit, citrus, tree nuts and potatoes that will offer broad-spectrum insect pest control.
- Potatoes ― Colorado potato beetle, potato leafhopper
- Tree fruit ― Asian citrus psyllid, codling moth, mites, oriental fruit moth, pear psylla, plum curculio, thrips
- Tree nuts ― Mites
While the above-listed pests are proposed key targets, the proposed labels will be for a range of pests beyond those mentioned.
Syngenta previously announced the brand names for its corn and seed treatment insecticide brands, Opello™ and Equento®, designed to manage corn rootworm and other soil-dwelling insect pests. All five insecticide brands will contain isocycloseram, which will be marketed under the trademarked name PLINAZOLIN technology.
For more technical information, visit www.PLINAZOLINtechnology.com or reach out to your local Syngenta representative. Join the conversation online ― connect with Syngenta at Syngenta-US.com/social.
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About Syngenta Crop Protection
Syngenta is a global leader in agricultural innovation with a presence in more than 100 countries. Syngenta is focused on developing technologies and farming practices that empower farmers, so they can make the transformation required to feed the world’s population while preserving our planet. Its bold scientific discoveries deliver better benefits for farmers and society on a bigger scale than ever before. Guided by its Sustainability Priorities, Syngenta is developing new technologies and solutions that support farmers to grow healthier plants in healthier soil with a higher yield. Syngenta Crop Protection is headquartered in Basel, Switzerland; Syngenta Seeds is headquartered in the United States. Read our stories and follow us on LinkedIn, Instagram & X.
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© 2025 Syngenta. 410 Swing Road, Greensboro, NC 27409. Important: Always read and follow label instructions. Some products may not be registered for sale or use in all states or counties. Please check with your local extension service to ensure registration status. Equento, Incipio, Opello, PLINAZOLIN, Vertento and Zivalgo are not yet registered for sale or use in the United States and are not being offered for sale. Equento®, Incipio™, Opello™, PLINAZOLIN®, Vertento®, Zivalgo™ and the Syngenta logo are trademarks of a Syngenta Group Company. All other trademarks are the property of their respective owners.